Digestive system ~18% lower CRC incidence*
Colonoscopy can detect and remove polypsMain indicators
Colorectal screening, upper-GI inflammation, reflux-related concerns, polyps, biopsy routing and stool-based risk signals where appropriate.
Screening logic
Digestive screening is useful when it combines direct visual assessment, biopsy routing and provider-led interpretation instead of relying on blood markers alone.
Patient benefit
Endoscopy is actionable: suspicious findings can be biopsied, and suitable polyps may be removed in the same pathway when the provider considers it appropriate.
Evidence base
* In the NordICC randomised trial (Bretthauer et al., NEJM 2022), invitation to screening colonoscopy was associated with about 18% lower colorectal-cancer incidence over 10 years. The primary analysis did not show a significant reduction in colorectal-cancer mortality.
